Sesame - lipid support for the skin
Sesame (Sesamum indicum) is one of the oldest oilseed plants used by humans. For centuries, it has been valued not only in nutrition but also in skin care. Modern cosmetology...
Klinicznie udowodnione Clinically proven
Randomizowane badanie z podwójnym zaślepieniem i grupą placebo. 60 ochotników, 6 miesięcy obserwacji, wyniki potwierdzone przez niezależny panel ekspertów. Randomized, double-blind, placebo-controlled clinical trial. 60 volunteers, 6 months of observation, results confirmed by an independent expert panel.
Efekt estetyczny w czasie — ocena niezależnych ekspertów Aesthetic effect over time — independent expert evaluation
Obie grupy otrzymały zabieg z toksyną botulinową. Następnie przez 6 miesięcy stosowały krem — jedna z konotoksyną, druga bez (placebo). Od dnia 90. różnica rośnie na korzyść konotoksyny. Both groups received a botulinum toxin treatment. Then for 6 months they used a cream — one with conotoxin, the other without (placebo). From day 90, the difference grows in favor of conotoxin.
Różnice statystycznie istotne (p<0.05) od dnia 90. W dniu 180 p≈0.0000 — najwyższa istotność. Skala 1–5, ocena efektu estetycznego przez niezależny panel ekspertów na podstawie medycznej dokumentacji fotograficznej. Statistically significant differences (p<0.05) from day 90. At day 180, p≈0.0000 — highest significance. Scale 1–5, aesthetic effect evaluation by an independent expert panel based on medical photographic documentation.
test t-Studenta, p<0.001 od dnia 135 Student's t-test, p<0.001 from day 135Efekty konotoksyny Conotoxin effects
vs placebo, ocena ekspertów, 180 dni vs placebo, expert evaluation, 180 days
istotne od dnia 105, brak efektu w placebo significant from day 105, no effect in placebo
istotne od dnia 60, brak efektu w placebo significant from day 60, no effect in placebo
Efekty bazy kremowej Cream base effects
pomiary kutometryczne, obie grupy, 180 dni corneometer measurements, both groups, 180 days
pomiary kutometryczne, 180 dni, p<0.001 corneometer measurements, 180 days, p<0.001
obie grupy porównywalnie — efekt bazy both groups comparable — base formula effect
Profil bezpieczeństwa >95% Safety profile >95%
Reakcje skórne u mniej niż 5% uczestników, przypisane iniekcji toksyny botulinowej. Objawy uboczne (swędzenie, pieczenie, zdrętwienie) występowały częściej w grupie placebo niż w grupie stosującej krem z konotoksyną. Skin reactions in fewer than 5% of participants, attributed to the botulinum toxin injection. Side effects (itching, burning, numbness) occurred more frequently in the placebo group than in the conotoxin cream group.
Badanie: K-LAB Badania i Rozwój, Gdynia · Standard ISO 14155:2020 · Główny badacz: dr n. med. Paweł Kubik · 60 ochotników (30+30), wiek 30–68 lat · Randomizacja + podwójne zaślepienie · Toksyna botulinowa 20j. + krem 2×/dziennie przez 180 dni · Pomiary: kutometr Multi Skin Test Centre 1000, dokumentacja foto FotoMedicus · Pozytywna opinia Komisji Bioetycznej przy OIL w Gdańsku · REP/1/4/S4B/K-LAB/2023/PL Study: K-LAB Research & Development, Gdynia, Poland · ISO 14155:2020 standard · Principal investigator: Paweł Kubik, MD, PhD · 60 volunteers (30+30), age 30–68 · Randomized + double-blinded · Botulinum toxin 20u + cream 2×/day for 180 days · Measurements: corneometer Multi Skin Test Centre 1000, FotoMedicus photo documentation · Bioethics Committee approval, Gdańsk · REP/1/4/S4B/K-LAB/2023/PL
Application test results after 28 days of using Miorelaxant Magic™ cream twice a day by a group of 60 volunteers.
Dr. Agnieszka Lew-Mirska Self Esteem Aesthetic Clinic“MIORELAXANT MAGIC is a unique product that combines all the features of an ideal cosmetic: innovation, effectiveness, safety and pleasure of use. I am extremely proud that my clinic was the first to offer this product to patients, and from the very moment it entered the market, they could supplement the treatment plans I created with this unique cosmeceutical.
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Paweł Kubik, M.D. Dr. Kubik Medical Center“The most interesting thing is that this cream really works!”
Katarzyna Daniłko/Quality lady“I have a great cream to recommend (...) I told you several times that there is a cream that prolongs the action of botulinum toxin and it actually does, for the first time in my life I felt tension on my skin after using the cream. Generally speaking, it always seemed to me that it was impossible to achieve (...) I must tell you that it is the best, but it is absolutely the best cream that I have ever tested in my life.
Dr. Przemysław Styczeń Aesthetic Medicine Clinic Dr. Przemysław Styczeń“So far, I have not come across a cosmetic that would give results visible to the naked eye. Some volunteers taking part in the study observed the reduction of even deep wrinkles. I'm impressed."
Dr Kamila Koska-Mach Clinic of Aesthetic Medicine and Cosmetology Kosma“At the beginning, when my friends recommended MIORELAXANT MAGIC to me, I approached it without conviction. Before I introduced this preparation to my patients, I tested it myself. From that moment on, it has been a permanent element of my work with botulinum toxin - it noticeably prolongs its effect and thus the patient's satisfaction with the procedure."
Dr. Anna Butowska Aesthetic Medicine Anna Butowska“The cream is a perfect solution for those who, for some reason, are afraid of botulinum toxin and would like to reduce wrinkles, and for those who are already using the toxin and would like to strengthen its effect and enjoy a younger appearance.The most interesting thing is that this cream really works!”
Katarzyna Krauss DAMOSPHEREI highly recommend it! It's phenomenal!
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